The school was chartered in 1994 but closed due to the closure of its parent institution, the Picower Institute.[2] In 2001, the school was acquired by the North Shore-LIJ Institute for Medical Research and revived as the North Shore LIJ Graduate School of Molecular Medicine and again to the Elmezzi Graduate School of Molecular Medicine in 2008.[3] The latter renaming took place after a $15 million donation from the Thomas and Jeanne Elmezzi Private Foundation.[4] As of 2020, the school has 41 graduates.[3]