Elizaveta was born on 20 December 1985 in Leningrad to a family of two famous Soviet actors Mikhail Boyarsky and Larisa Luppian. Her father is of Russian and Polish descent and her mother is of Estonian, German, Russian and Polish ancestry. As a teenager, she graduated from a modeling school. In secondary school she struggled with her studies, but during the last few years she caught up due to private coaching. Because of this, Elizaveta acquired the knowledge of two foreign languages – English and German. When she was about to graduate, Elizaveta was interested in studying "Public relations" at the Faculty of Journalism at the Saint Petersburg State University. But after attending preparatory courses she lost interest in the field. After visiting the opening of the student theater "On Mokhovoy" and several productions Theatre Lensoveta, Elizaveta decided to enter the Theatre Institute. As Boyarskaya herself later recalled, her parents did not dissuade from such a choice, but warned "about all the hidden obstacles".
Since 2006 she has worked at the Maly Drama Theatre (Theatre of Europe) in St. Petersburg.
She made her debut in 2001 in the sequel film National Security Agent 3, and in 2004 acted in the German film Downfall.
Her first major role in film was the role of Tanya in the film The First After God, directed by Vasily Chiginsky (2005). Another significant role was that of Vera in the film You Will not Leave Me, directed by Alla Surikova, in which Boyarskaya acted together with her father, Mikhail Boyarsky. She received wide popularity with the 2006 film Park of the Soviet Period and Timur Bekmambetov's movie The Irony of Fate 2 (2007).
It was planned that in the film The Return of the Musketeers, or The Treasures of Cardinal Mazarin Boyarskaya would play the role of daughter of d'Artagnan, but later this role was performed by Lyanka Gryu.[4] She refused this role, because at the same time she simultaneously starred in the film The Admiral and in the 12-episode series I Will Return. In addition, she said she did not find the script by Yungvald-Khilkevich particularly impressive.[5]