Construction of this church was begun in the 13th-century at the site of a small castle-associated church called Santa Maria in Castello. The church has undergone various restorations over the centuries, and its facade now has an eclectic neo-classical style. In prior centuries, the church had been owned by the nearby Abbey of Farfa and had been elevated to a collegiate church. The Romanesque-style multi level bell-tower with mullioned windows stands apart from the church.
The interior contains a canvas depicting St Anne and the Virgin (Education of the Virgin) by Vincenzo Manenti[1] and a Crucifixion with the Virgin and St John attributed to followers of Guido Reni. The wooden tabernacle on the main altar was designed by Vignola. A The church has a curious crucifix, fashioned in the East, using human hair. The church has processional silver cross and wooden icon statue of Sant'Antonio in the sacristy.[2]
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