dynamin-related protein 1 (Drp1), is encoded by the DNM1L gene and is part of the dynamin superfamily (DSP) family of proteins. Drp1, which is a member of...

of Drp1, which regulate tissue-specific mitochondrial fission. Drp1 is involved in the fission of both mitochondria and peroxisomes. The folded Drp1 monomer...

was firstly identified as a mitofusin 2- and Drp1-binding protein. MARCH5 promotes ubiquitination of Drp1 and a knockdown of MARCH5 is by RNAi led to abnormal...

Drp1; the Mff-Drp1 complex is what promotes mitochondrial fission. Knockdown of Mff causes the mitochondrial network to expand (by releasing the Drp1...

to physically interact with the Drp1 protein. To recap, the MID51 and MID49 are both similar proteins that recruit Drp1 protein to induce mitochondrial...

the mitofusins, OPA1 regulates inner mitochondrial membrane fusion, and DRP1 is responsible for mitochondrial fission. Mitofusin-2 (MFN2) is a mitochondrial...

PKA signaling pathway regulates the phosphorylation and localization of DRP1 within mitochondria of the steroidogenic cells of the ovary. GCSE Science...

mutations in both Drp1, a mitochondrial fission factor, and PINK1 were fatal in Drosophila models. However, an over-expression of Drp1 could rescue subjects...

Cieplak P, Cho DH, Godzik A, Lipton SA (August 2010). "S-nitrosylation of Drp1 links excessive mitochondrial fission to neuronal injury in neurodegeneration"...

location. These include: Mitochondrial fission regulation by inhibition of Drp1. GFER, acts as an augmentor of liver regeneration. GFER interacts with various...

Michael GJ, Giunti P, Vermeer S, Chapple JP (June 2016). "A reduction in Drp1-mediated fission compromises mitochondrial health in autosomal recessive...

involved in mitochondrial fission via binding dynamin-related protein 1 (DRP1). By extension, FIS1 helps regulate the size and distribution of mitochondria...

the dynamin family. The process of mitochondrial fission is directed by Drp1, a member of the cytosolic dynamin family. This protein forms a spiral around...

mitochondrial fission. These groups of proteins include mitofusins, OPA1/Mgm1, and Drp1/Dnm1. All of these molecules are GTP hydrolyzing proteins (GTPases) that...

dynamin-related protein 1 (Drp1) to block the translocation of Drp1 to the mitochondria which lead to an attenuation of the Drp1 dependent mitochondrial...

Dynamin-related protein 1 (Drp1) is an essential element in mitochondrial fission. Cdk5 can alter the subcellular distribution of Drp1 and its activity. As...

shown to be independent from the mitochondrial fission and fusion regulators DRP1 and OPA1. The phomoxanthones are named after the fungus Phomopsis, from which...

neurodegenerative diseases like AD. This SNO-Cdk5 in turn is nitrosylated Drp1, the nitrosylated form of which can be considered as a therapeutic target...

Dillin, Andrew; Mercola, Mark; Ronai, Ze'ev A. (2011-11-18). "Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to...

Jerzy; Hołyst, Robert (2019). "Determination of oligomerization state of Drp1 protein in living cells at nanomolar concentrations". Scientific Reports...

abnormal phosphorylation of the fission mediator dynamin-related protein 1 (DRP1), resulting in mitochondria that are smaller, more numerous, and fragmented...

catalytically dead but binds GDP or ADP, is part of a complex that recruits Drp1 to mediate mitochondrial fission. CENP-M cannot bind GTP or switch conformations...

shown to regulate mitochondrial fission by interacting with the proteins Drp1 and FIS1. GRCh38: Ensembl release 89: ENSG00000100335 – Ensembl, May 2017...

CRMP1 Identifiers Aliases CRMP1, CRMP-1, DPYSL1, DRP-1, DRP1, ULIP-3, collapsin response mediator protein 1 External IDs OMIM: 602462; MGI: 107793; GeneCards:...

mitochondrial fission and following mitophagy. HBV stimulates the phosphorylation of Drp1, a fission-promoting GTPase molecule, and the expression and recruitment...

UTRN Identifiers Aliases UTRN, DMDL, DRP, DRP1, utrophin External IDs OMIM: 128240; MGI: 104631; GeneCards: UTRN Available structures PDB Human UniProt...

dynactin/dynein targeting to the nuclear envelope before mitosis. Actr10 along with Drp1 (Dynamin related protein 1) have been documented as vital to the attachment...

mycobacteria with the help of other mitochondrial fission proteins such as DRP1 and FIs1. Under certain conditions, mitochondrial fission and its associated...

mitochondrial fission through the retention of inactive dynamin related protein 1 (Drp1) in the outer mitochondrial membrane. Thiophene thiourea derivatives R33...

These functions then allow DNAJA3 to mediate mitochondrial fission through DRP1 and, by extension, cellular processes such as cell movement, growth, proliferation...

regulates mitochondrial morphology by affecting mitochondrial recruitment of Drp1". FEBS Letters. 589 (20 Pt B): 3126–32. doi:10.1016/j.febslet.2015.08.039...

DENR Identifiers Aliases DENR, DRP, DRP1, SMAP-3, density-regulated protein, density regulated re-initiation and release factor External IDs OMIM: 604550;...

DAPK2 Identifiers Aliases DAPK2, DRP-1, DRP1, death-associated protein kinase 2, death associated protein kinase 2 External IDs OMIM: 616567; MGI: 1341297;...