"The Stroke" was the first single, reaching number 17 on the Billboard Hot 100, and an even bigger hit at rock radio, hitting number 3 on the Mainstream Rock chart. The song even dented the British Pop charts, rising to number 52. The video for "The Stroke" — as most of the music videos from both Don't Say No and its follow-up, Emotions In Motion — is a straight-ahead performance piece, featuring Squier on an arena stage. Billy's many videos were staples on the then brand-new channel known as MTV which brought him increased popularity.
"In the Dark" followed "The Stroke" into the Billboard Top 40, and the Top 10 of the Album Rock Tracks chart. Some other tracks from the album were also hugely popular on AOR (Album Oriented Rock) radio stations, for example, "Lonely Is the Night", which became subsequently one of his signature songs despite not being a proper single release or having a music video.
The album was certified Gold by the RIAA for 500,000 sales in July 1981 and Platinum two months later. Though multi-platinum awards were not certified prior to 1984, Don't Say No belatedly received a Triple Platinum award in 1992, certifying sales of over 3 million US copies.
On July 27, 2010 Shout! Factory released a 30th Anniversary edition of the album complete with newly remastered sound, bonus tracks, and a new booklet.
In early 2018, Intervention Records reissued Don't Say No on 180-gram vinyl and SACD/CD.[3] The reissue is Artist-Approved and according to Squier "arguably the best-sounding version ever."[4]