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Diffractaic acid

Diffractaic acid
Names
IUPAC name
4-(2,4-dimethoxy-3,6-dimethylbenzoyl)oxy-2-hydroxy-3,6-dimethylbenzoic acid[1]
Other names
Diffractic acid,[1] Dirbizomic acid,[1] Dirhizomic acid,[1] NSC 5901,[2] NSC 685595[2]
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C20H22O7/c1-9-8-14(11(3)17(21)15(9)19(22)23)27-20(24)16-10(2)7-13(25-5)12(4)18(16)26-6/h7-8,21H,1-6H3,(H,22,23)
    Key: MIJKZXWOOXIEEU-UHFFFAOYSA-N[2]
  • O=C(O)C1=C(O)C(C)=C(OC(C2=C(OC)C(C)=C(OC)C=C2C)=O)C=C1C
Properties
C20H22O7
Molar mass 374.389 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Diffractaic acid is a β-orcinol depside with the molecular formula C20H22O7, which is produced by lichens.[3][1][4] Diffractaic acid has cytotoxic, cytogenetic, oxidative, analgesic and antiviral effects.[4]

The foliose lichen species Punctelia diffractaica is named for the presence of this compound.[5]

References

  1. ^ a b c d e "Diffractaic acid". Pubchem.ncbi.NLM.nih.gov.
  2. ^ a b c "Diffractaic Acid (CAS 436-32-8)". www.caymanchem.com.
  3. ^ Sukumaran, Swapna Thacheril; Sugathan, Shiburaj; Abdulhameed, Sabu (28 November 2020). Plant Metabolites: Methods, Applications and Prospects. Springer Nature. p. 265. ISBN 978-981-15-5136-9.
  4. ^ a b Demir, Leyla; Toğar, Başak; Türkez, Hasan; Sozio, Piera; Aslan, Ali; Stefano, Antonio Di (2015). "The investigation of cytogenetic and oxidative effects of diffractaic acid on human lymphocyte cultures". Brazilian Archives of Biology and Technology. 58: 75–81. doi:10.1590/S1516-8913201502752. ISSN 1516-8913.
  5. ^ Kurokawa, S. (1999). "Notes on Flavopunctelia and Punctelia (Parmeliaceae), with descriptions of four new species". Bulletin of the Botanical Garden of Toyama. 4: 25–32.

Further reading

  • Sinha, Rajeshwar P.; Häder, h c Donat-P. (6 October 2020). Natural Bioactive Compounds: Technological Advancements. Academic Press. p. 257. ISBN 978-0-12-820659-1.


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