Cajuste attended Stanford University, where he played on the Stanford Cardinal football team from 2011 to 2015.[1] In his college football career, he recorded 90 receptions for 1,589 yards and 14 touchdowns.
After going undrafted in the 2016 NFL draft, Cajuste signed with the San Francisco 49ers on May 6, 2016.[4] On September 3, 2016, he was released by the 49ers during final team cuts.[5]
On January 31, 2018, Cajuste signed a reserve/future contract with the Cleveland Browns.[7] Cajuste quickly became a star on Hard Knocks. Fan support for Cajuste became known after sharing a story about his father and the ups and downs they overcame to make his NFL career a reality. Cajuste was waived by the Browns on September 1, 2018 during roster reductions.[8]
On January 31, 2019, Cajuste announced his retirement from the NFL due to physical and mental weakness and to pursue spiritual healing and his passion for crystals.[9]