The Churnet Valley line was authorised in 1846 and opened to traffic between Macclesfield and Uttoxeter in 1849. Denstone did not originally have a station but in 1873 a station was opened at the site of the College Road level crossing. As it had been built at the crossing the station was called Denstone Crossing. In 1923 one of the last acts of the NSR before it became part of the LMS was to rename the station simply Denstone.
The platforms remain in situ as part of a footpath to Oakamoor via Alton Towers but a house has been built across the route of the line, adjoining the former level crossing.