Defrag may refer to:

• Defragmentation, in the context of maintaining computer file systems, is a process that reduces the number of pieces of a file and/or the scattered available areas.
• DEFRAG, DOS and Windows 9x-systems FAT defragmentation utility
• DeFRaG, unofficial Quake III Arena video game modification

• List of defragmentation software
• Comparison of defragmentation software

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