In 1989 and 1990, Ison was a prehearing attorney for the Michigan Court of Appeals. In 2002, Ison began serving as an assistant United States attorney in the United States Attorney's Office for the Eastern District of Michigan. She also served as chief of the Drug Enforcement Task Force Unit.[3][4]
United States attorney for the Eastern District of Michigan
On November 12, 2021, President Biden nominated Ison to be the United States Attorney for the Eastern District of Michigan.[3] She was reported out favorably by the Senate Judiciary Committee on December 9, 2021, and was confirmed by the Senate on December 14, 2021.[5] She was sworn into office on December 21, 2021.[6]