As of January 2015, there are 24 legitimate clubs registered with the Davao-South Regional FA, 23 of which are based in Davao City. The other club team that is registered with the Association outside of Davao is from Davao del Sur. All registered clubs under the Association are sanctioned by the Philippine Football Federation.
1. A.L. Navarro NHS FC
2. Black Knights FC
3. Bansalan FC
4. Crocs FC
5. D'Davao Survivors FC
6. Davao Hyenas FC
7. Davao Grassroots Champions League (DGCL) FC
8. DRFA Coaches Association
9. DRFA Referee's Association
10. First Companions FC
11. Green Strikers FC
12. Hexamindz FC
13. KTMSCES FC
14. Lady Knights FC
15. Oi Rogers FC
16. PCT-Medvil FC
17. PTA Boys FC
18. Rovers FC Davao
19. RMC FC
20. Sakya FC
21. SOS FC
22. Southshield FC
23. UM FC
24. UP Mindanao FC
Registered and legitimate members as of December 2018