In 1997, Glišić joined the far-rightSerbian Radical Party (SRS) and was elected vice-president of the party's Kolubara District branch. In 2000, he was elected president of the SRS's Kolubara District branch. He served as the president of the Assembly of the Municipality of Ub from 2005 to 2006[2] and was a member of the National Assembly from 2004 to 2008.[1]
SRS split later in 2008, and Glišić was one of the founders of the populistSerbian Progressive Party (SNS) led by Tomislav Nikolić and Aleksandar Vučić. He is a close associate and confidant of President Aleksandar Vučić.[3] Since 2012, Glišić has been serving as the mayor of Ub.[1][4] In 2016, Glišić was elected president of SNS's executive board succeeding Radomir Nikolić.[5][6] He has been described as one of the most powerful people in SNS[7] and its key operative.[4]
In May 2023, during the ongoing protests, Glišić said that the actors who are against the regime "should go act somewhere else".[8] Actor Petar Božović reacted by saying that Glišić's statement has "traces of fascism".[9] His statements were also criticized by actors Nikola Kojo and Dragan Bjelogrlić.[10][11] On 4 June 2023, Glišić insulted government minister Rade Basta, calling him a "NATO scum".[12]