Daphnoretin

Daphnoretin
Names
Preferred IUPAC name
7-Hydroxy-6-methoxy-3-[(2-oxo-2H-1-benzopyran-7-yl)oxy]-2H-1-benzopyran-2-one
Other names
Thymelol
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C19H12O7/c1-23-16-6-11-7-17(19(22)26-15(11)9-13(16)20)24-12-4-2-10-3-5-18(21)25-14(10)8-12/h2-9,20H,1H3
    Key: JRHMMVBOTXEHGJ-UHFFFAOYSA-N
  • InChI=1/C19H12O7/c1-23-16-6-11-7-17(19(22)26-15(11)9-13(16)20)24-12-4-2-10-3-5-18(21)25-14(10)8-12/h2-9,20H,1H3
    Key: JRHMMVBOTXEHGJ-UHFFFAOYAG
  • COC1=C(C=C2C(=C1)C=C(C(=O)O2)OC3=CC4=C(C=C3)C=CC(=O)O4)O
Properties
C19H12O7
Molar mass 352.298 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Daphnoretin is a protein kinase C activator isolated from Wikstroemia indica C.A. Mey, one of the 50 fundamental herbs in traditional Chinese medicine.[1][2] It has also been found to occur in Stellera chamaejasme - the single species in a genus closely related to Wikstroemia within the family Thymelaceae.[3]

References

  1. ^ Gu, Shoubin; He, Jinhai (January 9, 2012). "Daphnoretin induces cell cycle arrest and apoptosis in human osteosarcoma (HOS) cells". Molecules. 17 (1). MDPI: 598–612. doi:10.3390/molecules17010598. PMC 6268824. PMID 22231496.
  2. ^ Ko, Feng N.; Chang, Ya L.; Kuo, Yueh H.; Lin, Yun L.; Teng, Che M. (October 1, 1993). "Daphnoretin, a new protein kinase C activator isolated from Wikstroemia indica C.A. Mey". Biochemical Journal. 295 (1). Portland Press Limited: 321–327. doi:10.1042/bj2950321. PMC 1134857. PMID 8216237.
  3. ^ Medicinal Plants in Mongolia pub. World Health Organization, Regional Office for the Western Pacific Region 2013 ISBN 978 92 9061 632 0 [1]


Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

  1. The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
  2. There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
  3. It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
  4. Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
  5. Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.