He was ordained as a deacon on 26 August 1979, and as a priest on 14 September 1980. He was a parish priest until his appointment to be archdeacon of Sunyani in 1986, and became a canon of Kumasi cathedral in 1994. He was a forces chaplain in the Ghanaian Army, holding the rank of major when he was elected the third bishop of the Diocese of Kumasi on 20 November 1998. He was consecrated on 14 March 1999. Sarfo was elected the first Metropolitan archbishop of the Internal Province of Ghana on its creation on 29 September 2012.[1] He automatically succeeded Solomon Tilewa Johnson, after his unexpected death, as Archbishop Primate of CPWA, by virtue of being the surviving metropolitan (according to the 2012 adaptation of the CPWA constitution). He was consecrated the 10th Primate of the Church of the Province of West Africa on 13 March 2014.