8788
13386
ENSG00000185559
ENSMUSG00000040856
P80370
Q09163
NM_001032997NM_003836NM_001317172
NM_001190703NM_001190704NM_001190705NM_010052
NP_001304101NP_003827NP_003827.3
NP_001177632NP_001177633NP_001177634NP_034182
Protein delta homolog 1, delta like non-canonical Notch ligand 1, fetal antigen 1[5] or preadipocyte factor 1[6] is a protein that in humans is encoded by the DLK1 gene.[7][8][9]
It is expressed as a transmembrane protein, but a soluble form cleaved off by ADAM17 is active in inhibiting adipogenesis,[10] the differentiation of pre-adipocytes into adipocytes.[11]
It is a member of the EGF-like family of homeotic proteins.[12]
Part of the Dlk1-DIO3 imprinting control region, this gene is one involved in the epigenetic process that causes a subset of genes to be regulated based on their parental origin.[13]
Such imprinted genes are required for the formation of the placenta as well as the development of cellular lineages such as those derived from the mesoderm and ectoderm.[14]
This article on a gene on human chromosome 14 is a stub. You can help Wikipedia by expanding it.
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