11258
53598
ENSG00000137100
ENSMUSG00000028447
O75935
Q9Z0Y1
NM_024348NM_001281425NM_001281426NM_001281427NM_007234
NM_001159565NM_016890
NP_001268354NP_001268355NP_001268356NP_009165NP_077324
NP_001153037NP_058586
Dynactin subunit 3 is a protein that in humans is encoded by the DCTN3 gene.[5][6][7]
This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates 2 transcript variants.[7]
This article on a gene on human chromosome 9 is a stub. You can help Wikipedia by expanding it.
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