The creek and its tributaries form a network of canyons cut into the horizontal basalt layers of the Blue Mountains. The entirety of the creek flows within the Wenaha-Tucannon Wilderness of the Umatilla National Forest. Its major tributaries, listed from upstream to downstream, are Third, Second, Cherry, Melton and First Creeks, all joining from the left.[2][4] The 19-mile (31 km) Crooked Creek Trail begins at the crest of the Blue Mountains at Indian Corral, and descends to the Wenaha River via Trout, Third and Crooked Creeks. Much of the area was burned during the 2015 Grizzly Bear Complex fire.[6][7]
It was historically called the "Crooked Fork" of the Wenaha River.[8]: 114