Colneleate synthase

Colneleate synthase
Identifiers
EC no.4.2.1.121
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

Colneleate synthase (EC 4.2.1.121, 9-divinyl ether synthase, 9-DES, CYP74D, CYP74D1, CYP74 cytochrome P-450, DES1) is an enzyme with systematic name (8E)-9-((1E,3E)-nona-1,3-dien-1-yloxy)non-8-enoate synthase.[1][2][3][4] This enzyme catalyses the following chemical reaction

(9S,10E,12Z)-9-hydroperoxyoctadeca-10,12-dienoate
(8E)-9-[(1E,3Z)-nona-1,3-dien-1-yloxy]non-8-enoate + H2O

This enzyme is a heme-thiolate protein (P450).

References

  1. ^ Stumpe M, Kandzia R, Göbel C, Rosahl S, Feussner I (November 2001). "A pathogen-inducible divinyl ether synthase (CYP74D) from elicitor-treated potato suspension cells". FEBS Letters. 507 (3): 371–6. doi:10.1016/s0014-5793(01)03019-8. PMID 11696374.
  2. ^ Itoh A, Howe GA (February 2001). "Molecular cloning of a divinyl ether synthase. Identification as a CYP74 cytochrome P-450". The Journal of Biological Chemistry. 276 (5): 3620–7. doi:10.1074/jbc.m008964200. PMID 11060314.
  3. ^ Fammartino A, Cardinale F, Göbel C, Mène-Saffrané L, Fournier J, Feussner I, Esquerré-Tugayé MT (January 2007). "Characterization of a divinyl ether biosynthetic pathway specifically associated with pathogenesis in tobacco". Plant Physiology. 143 (1): 378–88. doi:10.1104/pp.106.087304. PMC 1761965. PMID 17085514.
  4. ^ Hamberg M (February 2005). "Hidden stereospecificity in the biosynthesis of divinyl ether fatty acids". The FEBS Journal. 272 (3): 736–43. doi:10.1111/j.1742-4658.2004.04510.x. PMID 15670154.