A clostridial vaccine is a vaccine for sheep and cattle that protects against diseases caused by toxins produced by an infection with one or more Clostridium bacteria.[1] Clostridial vaccines are often administered to pregnant ewes a few weeks before they are due to give birth, in order to give passive immunity to their lambs.[1] Clostridial bacteria multiply rapidly in infected sheep, and produce large amounts of toxin which can cause the sheep to die within hours.[2]
Clostridial vaccines can contain anti-toxins to one or more endotoxins produced by the following bacteria:[1]
Clostridial vaccines which protect sheep against multiple clostridial diseases have been available since the 1950s.[3]
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