In 2008, he was named a Second Team College All-American and Big East Conference All-Star at third base, and Big East Conference Player of the Year.[3] After the season, he was drafted by the Colorado Rockies in the fifth round of the 2008 Major League Baseball Draft, but he opted to return to Louisville for another season. In the summer of 2008, he returned to the CCBL to play for the Hyannis Mets, where he was named a league all-star, and made headlines by crushing three home runs in a single game, the first CCBL player to accomplish the feat since baseball hall of famer Frank Thomas did it twenty years earlier.[4][5]
In 2009, he was named a First Team College All-American and Big East Conference All-Star third baseman and Big East Conference Player of the Year.[citation needed]
Dominguez was called up to the majors for the first time on September 1, 2014.[7] On September 21, 2014, Dominguez hit his first Major League home run off Ian Kennedy, accounting for the only runs of the game in an 8–2 loss to the San Diego Padres.
On February 4, 2015, Dominguez was released by the Giants.
Cincinnati Reds
On February 11, 2015, Dominguez signed a minor league contract that included an invitation to spring training with the Cincinnati Reds.[8] He spent time with both the Triple-A Louisville Bats and the Reds that season. He elected free agency on November 6, 2015.[9]
Boston Red Sox
On December 15, 2015, Dominguez signed a minor league contract with the Boston Red Sox that included an invitation to spring training.[10] He spent the entire 2016 season with the Triple-A Pawtucket Red Sox, playing in 77 games and hitting .241/.275/.439 with 13 home runs, 39 RBI, and 7 stolen bases. He elected free agency following the season on November 7, 2016.[11]
Chicago Cubs
Dominguez signed a minor league contract with the Chicago Cubs organization on January 16, 2017, which included an invite to spring training.[12] He spent the year with the Triple-A Iowa Cubs, playing in 102 games and hitting .284/.323/.443 with 11 home runs, 45 RBI, and 12 stolen bases. Dominguez elected free agency following the season on November 6.[13]
Washington Nationals
On December 19, 2017, Dominguez signed a minor league contract with the Washington Nationals. He played in 84 games for the Triple–A Syracuse Chiefs, batting .243/.293/.406 with nine home runs, 45 RBI, and seven stolen bases. Dominguez elected free agency following the season on November 2, 2018.[14]
Dominguez later re-signed with Washington on a minor league deal on March 14, 2019. Dominguez was released by the Nationals organization on May 25.
Coaching career
On June 13, 2022, Dominguez was named the head baseball coach of the Bellarmine Knights.[15]
National champion
Postseason invitational champion
Conference regular season champion
Conference regular season and conference tournament champion
Division regular season champion
Division regular season and conference tournament champion
Conference tournament champion