Lady Williams-Wynn
Charlotte, Lady Watkin Williams-Wynn, by Daniel Gardner, c. 1775
Born	Charlotte Grenville c. 1754 Llanforda, Oswestry, Shropshire, England
Died	29 September 1830
Spouse	Sir Watkin Williams-Wynn, 4th Baronet ​ ​ (m. 1771; died 1789)​
Children	8, including Watkin, Charles, and Henry
Parents	George Grenville Elizabeth Wyndham
Relatives	George Nugent-Temple-Grenville, 1st Marquess of Buckingham (brother) Thomas Grenville (brother) William Grenville, 1st Baron Grenville (brother)

Charlotte, Lady Williams-Wynn (née Grenville; c. 1754 – 29 September 1830), was a British aristocrat.

Williams-Wynn was born in Llanforda, Oswestry. She was the eldest child of the Prime Minister George Grenville and his wife, the former Elizabeth Wyndham, daughter of the Tory statesman Sir William Wyndham, 3rd Baronet. Lady Williams-Wynn was a first cousin of Prime Minister William Pitt through her paternal aunt Hester Grenville, who married William Pitt, 1st Earl of Chatham.

Her mother and father died in 1769 and 1770 respectively, and guardianship of their daughter Charlotte was assumed by George's elder brother, Richard Grenville-Temple, 2nd Earl Temple.^[1]

On 21 December 1771, she married, as his second wife, Sir Watkin Williams-Wynn, 4th Baronet, and became known as Lady Williams-Wynn. Sir Watkin was the eldest son of Sir Watkin Williams-Wynn, 3rd Baronet, and his second wife, the former Frances Shackerley of Cheshire. The couple had eight children, six of whom survived to adulthood, including:

• Sir Watkin Williams-Wynn, 5th Baronet (1772–1840), who married Lady Henrietta Antonia Clive, eldest daughter of Edward Clive, 1st Earl of Powis and Henrietta Clive, Countess of Powis, in 1817.^[2]
• Frances Williams-Wynn (1773-1857), who remained unmarried, and whose political Diaries were published posthumously in 1864.^[3]
• Charlotte Williams-Wynn (1775–1819), who married Lt-Col William Shipley, MP for Flint Boroughs and St Mawes, and son of Very Rev. William Davies Shipley.^[2]
• Charles Williams-Wynn (1775–1850), who married Mary Cunliffe, daughter of Sir Foster Cunliffe, 3rd Baronet and Harriet Kinloch, in 1806.^[2]
• Henrietta Elizabeth Williams-Wynn (1780–1852), who married Thomas Cholmondeley, 1st Baron Delamere of Vale Royal.^[2]
• Sir Henry Williams-Wynn (1783–1856), who married Hon. Hester Frances Smith, daughter of Robert Smith, 1st Baron Carrington, in 1813.^[2]

Sir Watkin died on 24 July 1789. Upon her husband's death, Lady Williams-Wynn became the sole administrator of his Welsh estates under the terms of his will, and functioned as such until her eldest son reached the age of majority.

• Charlotte (Grenville), Lady Williams-Wynn (1754-1830) and her Children at Amgueddfa Cymru
• Charlotte, Lady Williams-Wynn at the British Museum