In June 1926, the Charles Stewart Mott Foundation was founded by C.S. Mott.[6] Starting in 1928, the foundation made annual gifts to the Flint Institute of Arts. With the establishment of the Flint Cultural Center in 1958, this annual contribution was shifted to the cultural center.[7]
In 1968, the Genesee County park system was started with the purchase of vacant land[8] funded by the Charles Stewart Mott Foundation with a stipulation that a parks commission be formed.[9]
Mott transferred U.S. Sugar shares to the foundation. In 1969 with a law passed limiting what private family foundations could hold of a corporation, the foundation gave a large number of shares to the Mott Children's Health Center, a Flint charitable medical organization founded in 1939, to be below the 35% limit.[10]
In June 2017, the foundation's 91st year, the Mott Foundation had surpassed over $1 billion in grants dispersed.[6]
In November 2018, the CEO, William White announced his immediate retirement and replacement by Ridgeway White as successor.[11][12] White died in October 2019, aged 82.[13]