Sherr received his AB from Oberlin College and his MD/PhD from New York University in 1972. He did a residency in pathology at Bellevue Hospital. After one year, he joined the US Public Health Service and the National Cancer Institute in 1973, and was hired as staff in 1975. In 1977, he became head of the viral pathology section of the Division of Cancer Cause and Prevention.[4] He relocated to St Jude in 1983, and became an HHMI Investigator in 1988.[3] He has received several awards for his research in cyclin-dependent kinases and their role in cell cycle and cancer growth.[5]
He is married to Martine Roussel, a biologist, and has 3 children.[1]