The station logo represents the caduceus, a variant of the Rod of Aesculapius, the Greek god of medicine.[2] Its name refers to the Centro Médico Siglo XXI general hospital, located above the metro station.[4][5][6] The station opened along Line 3 on 7 June 1980 when Centro Médico served briefly as the southern terminus of that line.[7] Line 3 service then extended further southward toward Zapata a year later by 25 August 1980.[7] The Centro Médico Siglo XXI was almost destroyed by the 1985 earthquake.[8] The station served as the western terminus of Line 9 (which went east towards Pantitlán) starting on 26 August 1987.[7] Westward service on Line 9 toward Tacubaya started a year later on 29 August 1988.[7]
The station is directly connected to the main entrance of Centro Médico by a set of escalators. This metro station has facilities for the handicapped, a cultural display, and an information desk.[2]
Centro Médico serves the Roma Sur, Doctores and Buenos Aires neighbourhoods.[2] It is located at the intersection of Avenida Cuauhtemoc and Eje 3 Sur Baja California, just a block north of Viaducto Miguel Alemán, an important east-west highway.[9][10] The southern exits at the Line 3 end of the station are close to the historic Panteón Francés (French Cemetery) in which important civil and military Mexican figures are buried.[9][10][11]
^"Localización" (in Spanish). La Unidad Medica de Alta Expecialidad Hospital de Pediatria del Centro Médico Nacional Siglo XXI. Retrieved 29 July 2011.
^ ab"Afluencia de estación por línea 2021" [Station traffic per line 2021] (in Spanish). Sistema Transporte Colectivo Metro. 2020. Archived from the original on 7 March 2022. Retrieved 7 March 2022.
^ ab"Afluencia de estación por línea 2020" [Station traffic per line 2020] (in Spanish). Sistema Transporte Colectivo Metro. 2021. Archived from the original on 21 June 2021. Retrieved 21 June 2021.