Cencenighe Agordino (Ladin: Zenzenìghe) is a comune (municipality) in the Province of Belluno in the Italian region Veneto, located about 110 kilometres (68 mi) north of Venice and about 30 kilometres (19 mi) northwest of Belluno.
Cencenighe Agordino borders the following municipalities: Canale d'Agordo, San Tomaso Agordino, Taibon Agordino, Vallada Agordina.
Cencenighe Agordino is twinned with:
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