Vessels of the uterus and its appendages, rear view. (Cardinal ligament not visible, but location can be inferred from position of uterine artery and uterine vein.)
Uterus and right broad ligament, seen from behind. (Cardinal ligament not labeled, but broad ligament visible at center.)
The cardinal ligament (also transverse cervical ligament, lateral cervical ligament,[1] or Mackenrodt's ligament[2][1]) is a major ligament of the uterus formed as a thickening of connective tissue of the base of the broad ligament of the uterus. It extends laterally (on either side) from the cervix and vaginal fornix to attach onto the lateral wall of the pelvis. The female ureter, uterine artery, and inferior hypogastric (nervous) plexus course within the cardinal ligament. The cardinal ligament supports the uterus.[1]
Structure
The cardinal ligament is a paired structure on the lateral side of the uterus. It originates from the lateral part of the cervix.[3]
It is continuous externally with the fibrous tissue surrounding the pelvic blood vessels.[4]
Function
The cardinal ligament supports the uterus, providing lateral stability to the cervix.[1]
Clinical significance
The cardinal ligament may be affected in hysterectomy.[5][6] Due to its proximity to the ureters, it can get damaged during ligation of the ligament. It is routinely cut during some uterine operations, although this can have side effects.[3]
^ abKyung Won, PhD. Chung (2005). Gross Anatomy (Board Review). Hagerstown, MD: Lippincott Williams & Wilkins. p. 274. ISBN0-7817-5309-0.
^Kato T, Murakami G, Yabuki Y (2002). "Does the cardinal ligament of the uterus contain a nerve that should be preserved in radical hysterectomy?". Anat Sci Int. 77 (3): 161โ8. doi:10.1046/j.0022-7722.2002.00023.x. PMID12422408. S2CID43367709.