Respiratory hospital admissions associated with PM10 pollution in Utah, Salt Lake, and Cache Valleys (1991), An Association between Air Pollution and Mortality in Six U.S. Cities (1993), Particulate air pollution as a predictor of mortality in a prospective study of U.S. adults (1995).
Early in Pope's career he published a paper that made him an academic cornerstone of environmental science and policy called "Respiratory hospital admissions associated with PM10 pollution in Utah, Salt Lake, and Cache Valleys".[4] In Utah Valley, the Geneva Steel Mill generated large quantities of particulate matter, a byproduct of fossil fuel consumption. The mill was shut down temporarily in 1986-87 as U.S. Steel sold the facility to new ownership. Pope compiled hospital admissions data for the time before, during, and after the temporary closing of the mill and was the first to convincingly show the immediate health harms associated with atmospheric particulate matter.[5]Asthma, mortality, and respiratory admissions generally were twice as high while the plant was operating than the year in which it was closed. Utah made a particularly suitable natural experiment as the various valleys included in the study trap pollution in the winter months when temperature inversions stifle the escape of pollution. His abstract states:
This study assessed the association between respiratory hospital admissions and PM10 pollution in Utah, Salt Lake, and Cache valleys during April 1985 through March 1989. Utah and Salt Lake valleys had high levels of PM10 pollution that violated both the annual and 24-h standards issued by the Environmental Protection Agency (EPA). Much lower PM10 levels occurred in the Cache Valley. Utah Valley experienced the intermittent operation of its primary source of PM10 pollution: an integrated steel mill. Bronchitis and asthma admissions for preschool-age children were approximately twice as frequent in Utah Valley when the steel mill was operating versus when it was not. Similar differences were not observed in Salt Lake or Cache valleys. Even though Cache Valley had higher smoking rates and lower temperatures in winter than did Utah Valley, per capita bronchitis and asthma admissions for all ages were approximately twice as high in Utah Valley. During the period when the steel mill was closed, differences in per capita admissions between Utah and Cache valleys narrowed considerably. Regression analysis also demonstrated a statistical association between respiratory hospital admissions and PM10 pollution. The results suggest that PM10 pollution plays a role in the incidence and severity of respiratory disease.
Pope came under political pressure and his findings provoked controversy.[6][7] Later scrutiny revealed his results were accurate.
Six Cities and American Cancer Society studies
Pope worked with Douglas Dockery of Harvard University on a 16-year scientific study of air pollution in six major cities in the United States, which published its findings in 1993.[8] Known as the Harvard Six Cities study, it proved to be a milestone in establishing the human health effects associated with long-term exposure to fine particulate pollution, and remains one of the most highly citied studies of air pollution ever published.[9] Like Pope's Utah Valley research, the Six Cities study proved intensely controversial.[10][11] The study's conclusions were affirmed in 2000 after a three-year-long independent analysis carried out by the Health Effects Institute.[12] They have also been supported by numerous follow-up studies.[13]
Pope and Dockery also collaborated on a long-term study of the effects of air pollution on over half a million people from 151 urban areas, which published its first results in 1995. Informally known as the American Cancer Society study, it found that long-term exposure to particulates was linked to cardiopulmonary and lung cancer mortality.[14]
^Brink, Susan (10 November 2013). "A Chinese Child's Lung Cancer Is Linked to Pollution". National Geographic. Archived from the original on November 8, 2013. We talked with C. Arden Pope, economics professor at Brigham Young University in Provo, Utah. His research into the effects of air pollution on human health and mortality has been instrumental in establishing federal air quality regulations.
^Harris, Gardiner (29 May 2015). "Holding Your Breath in India". New York Times. C. Arden Pope III, a professor of economics at Brigham Young University and a leading expert on the health consequences of air pollution...
^ abPope, C. A. (1991). "Respiratory hospital admissions associated with PM10 pollution in Utah, Salt Lake, and Cache Valleys". Archives of Environmental Health. 46 (2): 90–97. doi:10.1080/00039896.1991.9937434. PMID2006899.
^C.A. Pope, 1989. "Respiratory Disease Associated with Community Air Pollution and a Steel Mill, Utah Valley". American Journal of Public Health, May 1989, Vol. 79, No. 5, 623–628
^Pope, C. Arden; Thun, M.J.; Namboodiri, M.M.; Dockery, D.W.; Evans, J.S.; Speizer, F.E.; Heath, Jr., C.W. (March 1995). "Particulate air pollution as a predictor of mortality in a prospective study of U.S. adults". Am J Respir Crit Care Med. 151 (3_pt_1): 669–74. doi:10.1164/ajrccm/151.3_Pt_1.669. PMID7881654.
