For the 2013–2014 school year, the school offered 15 activities approved by the Missouri State High School Activities Association (MSHSAA): baseball, boys and girls basketball, sideline cheerleading, field hockey, 11-man football, music activities, boys and girls soccer, softball, speech and debate, boys and girls track and field, girls volleyball, and wrestling[5] In addition to its current activities, Brentwood students have won several state championships, including:
Football: Runner up 2009
Baseball: 1978, 1986
Girls basketball: 1985
Boys track and field: 1963, 1964, 1965, 1966, 1967, 1968, 1987, 1991[6]
This includes institutions outside of the city limits of St. Louis which have "St. Louis, MO" postal addresses. Note multiple places with "St. Louis, MO" postal addresses are not in the St. Louis city limits.