Bosio is a comune (municipality) in the Province of Alessandria in the Italian region Piedmont, located about 100 kilometres (62 mi) southeast of Turin and about 35 kilometres (22 mi) southeast of Alessandria.
Bosio borders the following municipalities: Campo Ligure, Campomorone, Casaleggio Boiro, Ceranesi, Gavi, Genoa, Lerma, Masone, Mele, Mornese, Parodi Ligure, Rossiglione, Tagliolo Monferrato, and Voltaggio.
The nearest point to the Ligurian Sea in Piedmont lies in the communal territory of Bosio, on Monte Biscia Mora, where the sea is just 8 km away; however, there is not a road directly connecting these locations.
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