Born in Waterloo, Iowa, Bowlsby was the AD at the University of Northern Iowa, until taking over as the athletic director at the University of Iowa from 1990 to 2006 prior to becoming Stanford's sixth athletic director in 2006.[3] In 2012, he was hired to be commissioner of the Big 12 Conference.[1] Bowlsby was selected as the NCAA Basketball Selection Committee Head in 2005. He was also a part of the United States Olympic Committee for the 2008 Summer Olympics in Beijing, China.
On April 5, 2022, Bowlsby announced his intention to step down as Big 12 Commissioner later in 2022.[4] On November 29, 2023, Bowlsby was announced to be the interim AD at the University of Northern Iowa. [5]
After his retirement, the Big 12 created the Bob Bowlsby Award in his honor. The award, voted on by Big 12 athletic directors, is presented to one men's and one women's athlete across all Big 12 sports and honors on- and off-field leadership and excellence. The Big 12 describes the award, first presented after the 2022–23 academic year, as "the Conference's most prestigious individual accolade".[6]