Enriquez was first a teacher's aide in 1973.[2] Enriquez later started teaching English as a second language to kindergartners and first graders in El Paso, Texas.[3] She became the head of the Region 19 Head Start program in 1986.[2] Enriquez served as the director of the El Paso region's Head Start program for 21 years.[4] Enriquez was named the director of the federal Head Start program in April 2015.[5]