As a true freshman at Arkansas State in 2017, Grupe redshirted.[3] The following year, he earned the starting placekicking job in week three and finished the season having converted 14-of-21 attempts, placing seventh in the Sun Belt Conference.[3] In 2019, Grupe made 19-of-22 field goal attempts and was named first-team all-conference as well as a semifinalist for the Lou Groza Award as best placekicker nationally; his 110 total points scored set a school record for kickers and was second-best in the conference, additionally being the 13th-best total in the United States.[5][6]
In 2020, Grupe went 11-of-18 on field goals and made 43 extra points.[6][7] In his final year at Arkansas State, 2021, he made 20-of-25 field goals and all but one of his 32 extra point attempts.[8] He holds several school records, including career extra points made (162), career field goals made (64) and career points scored (354).[9] Grupe transferred to Notre Dame for his final season of eligibility in 2022.[10] He went 14-of-19 on field goals and made all 49 of his extra point attempts in his lone year with the team.[11]
In Week 3 of the 2023 season, Grupe missed a 46-yard go-ahead field goal against the Green Bay Packers, resulting in a Saints loss.[18] In Week 5, Grupe was named National Football Conference Special Teams Player of the Week after completing four extra points, two 50+ yard field goals, and recording five touchbacks on seven kickoffs in a 34–0 win over the New England Patriots.[19] As a rookie, he converted all 40 extra point attempts and 30 of 37 field goal attempts.[20]