This article lists the winners and nominees for the Black Reel Award for Television for Outstanding Guest Actor, Drama Series. The category was first introduced as Outstanding Guest Performer, Drama Series, honoring both actors and actresses in guest starring roles on television. In 2018, the category was split into categories for each gender, resulting in the name change to its current title.

Winners are listed first and highlighted in bold.

• NBC - 2
• The CW - 1
• HBO - 1
• Netflix - 1