Twemlow played for Audley and Sandbach Ramblers before he joined Stoke in 1915.[1] He played for Stoke during World War I, featuring once in 1915–16, six times in 1916–17, 37 times in 1917–18, and 26 times in 1918–19. Having been a first-time regular during the war, once League football was resumed in 1919, he was first choice full-back under managerArthur Shallcross.[1] In 1919–20 he played 34 times, scoring twice both penalties against Bristol City in November and Bury in February.[1] However, he lost his place to the veteran Tom Brittleton and only played three matches in 1920–21 and was released from his contract at the Victoria Ground at the end of the campaign.[1]