A native of Clearview, Oklahoma, Jefferson was the brother of Jeff Jefferson, also played in the Negro leagues.[1] Jefferson played with several teams from 1937 to 1948, spending the majority of his career with the Cleveland Buckeyes. He was the starting pitcher for the Buckeyes when they made it to the 1945 Negro World Series, starting Game 1 against the two-time defending champion Homestead Grays. He threw a complete game while allowing just six hits and one earned run while striking out four and walking two batters in a 2–1 win, and the Buckeyes would ultimately sweep the Grays in four games.[2]