Rand was born in Philadelphia and graduated from Jefferson in 1848. Rand had taught Eakins high school chemistry. From 1852 to 1864, Rand was secretary to the Academy of Natural Sciences. Rand later became the chair of chemistry at the Franklin Institute, the Philadelphia Medical College until its closure in 1861, and served as Dean of Jefferson Medical College from 1864 to May 1877. He retired at the age of fifty for health reasons.[2]