BPC-157 (also known as PL 14736) is an oligopeptide consisting of a chain of fifteen amino acids. It has the amino acid sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val.[1] This peptide has a molecular formula of C62H98N16O22. As of 2022, the peptide is banned by the World Anti-Doping Agency under the S0 category of non-exempt substances.[2]
Preclinical studies and limited clinical trials have indicated that BPC-157 may have cytoprotective, neuroprotective, and anti-inflammatory effects, and may accelerate tissue healing.[3][4][5][6]
Research
There are some tentative pre-clinical studies on animals and in vitro suggesting possible benefit in wound healing and bowel disorders although all of these studies come from a single research group.[7][8]
Unapproved marketing
BPC 157 is marketed in functional medicine, although, FDA approval is not issued yet for it to be used in standard medicine.[9]
References
^Jelovac N, Sikiric P, Rucman R, Petek M, Marovic A, Perovic D, et al. (August 1999). "Pentadecapeptide BPC 157 attenuates disturbances induced by neuroleptics: the effect on catalepsy and gastric ulcers in mice and rats". European Journal of Pharmacology. 379 (1): 19–31. doi:10.1016/S0014-2999(99)00486-0. PMID10499368.