Hirsch's work engages a variety of media, including installation, film, video, and photography.
In her preface to Negative Space: Orbiting Inner and Outer Experience curator and writer Melanie O'Brian states "Antonia Hirsch's practice testifies to a long-standing engagement with the quantitative, spatial, and syntactic systems that structure an understanding of our universe... Hirsch's work relates these ordering structures to embodied and visual experience, considering how the equivocal and often ideological nature of these representational systems is expressed through a level of abstraction."[3]
Antonia Hirsch (ed.), Intangible Economies (with contributions by Juan A. Gaitàn, Melanie Gilligan, Hadley + Maxwell, Candice Hopkins, Olaf Nicolai, Patricia Reed, Monika Szewczyk, and Jan Verwoert). Vancouver: Fillip, 2012. ISBN978-1-927354-03-2
Antonia Hirsch, Komma (After Dalton Trumbo's Johnny Got His Gun), (with essays by Maria Muhle and Kristina Lee Podesva). Vancouver: Fillip, 2011. ISBN978-0-9738133-9-5