Ann or Anne Hughes may refer to:

• Ann Hughes (judoka) (born 1960), British judoka
• Ann Hughes (politician) (born 1943), American politician from Illinois
• Ann Harriet Hughes (1852–1910), Welsh language novelist
• Anne Hughes (art patron) (1944–2021), American gallery owner, restaurateur and patron of the arts
• Anne Meiman Hughes (born 1965), American politician from Connecticut
• Anne Penny (1729–1784), née Hughes, British poet and translator
• Anne Hughes (diarist), author of The Diary of a Farmer's Wife 1796–1797 (also known as Anne Hughes' Diary)

Topics referred to by the same term

This disambiguation page lists articles about people with the same name.
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