In 2003, in Croatia, Lehotská appeared in a television advertisement for Coca-Cola.[2]
In 2004, Lehotská was the VJ for All Music and in the cast of "Spicy Tg";[3] she debuted as an actress in What Will Happen to Us of Giovanni Veronesi.[4] In 2005, she appeared in the film Fratello e padre.[5] Also in 2005, Lehotská was in the music videos of Vasco RossiBuoni o cattivi, Come stai, Un sensoE... and Señorita. On September 9, 2005, Rossi released the double DVD È solo un Rock 'n Roll show (with 12 music videos) with Lehotská as protagonist.[5]
From 2005 to 2008, she was a columnist for the television program Markette. In 2007, she was a finalist in Uno due tre stalla, reality show of Canale 5.[6][7]
In 2008, she played the role of Bibi in the film Albakiara directed by Stefano Salvati.[8] From 2008 to 2009 she has presented BO051 for 7 Gold;[9] in 2009 she is in the cast of fiction Giochi sporchi for Rai 4.[10]
From 2009 to 2010, Lehotská was a co-protagonist in Una cena di Natale quasi perfetta on Sky Uno,[11] and in Sugo, a television program on Rai 4.[5]
From 2009 to 2011, she was a co-protagonist in Chiambretti Night, a television program of Mediaset,[12][13][14] and in 2011 Lehotská was a co-protagonist in Chiambretti Sunday Show on Italia 1.[14]
In 2011, she has presented Circo Massimo on Rai 3/RSI La 2.[15][16] She was also the protagonist of music video Hayat Öpücüğü of Murat Boz.[17]
In 2013 Andrea Lehotská presented Cena je správna on TV JOJ. In 2017, she played the role of Regina in the film Friends by Chance directed by Francesco Bruni.