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In 1965–1974, Samoilenko worked as a senior research fellow at the Institute of Mathematics of the Academy of Sciences of the Ukrainian SSR and gave lectures at the Shevchenko Kyiv State University. In 1974, he obtained the professor degree. In 1978, he was elected to become a Corresponding Member of the Institute of Mathematics of the Academy of Sciences of the Ukrainian SSR. His monograph[1] brought him worldwide recognition. This monograph was written by Samoilenko together with his teachers, Academicians N. N. Bogolyubov and Mitropolskiy. Thirty six years later, Samoilenko reminisced, "In Kyiv, at the Institute of Mathematics, great scientists were my teachers... In many fields of science, they were 'trendsetters' on the scale of the Soviet Union. It is very important for a young scientist to belong to a serious scientific school. Probably, only in this case he has a chance to obtain results at the world level. The atmosphere of a good scientific school itself stimulates a young scientist to carry out his research work at the cutting edge of modern science. And if he suddenly opens a new direction in science, then his name immediately gains recognition".[2]
In 1974–1987, Samoilenko headed the Chair of Integral and Differential Equations of the Department of Mechanics and Mathematics at the Shevchenko Kyiv State University. These years were marked by especially high scientific activity of the chair. Based on results of the research in the theory of differential equations with delay performed at that time, the monograph[3] of Mitropolskiy, Samoilenko, and D. I. Martynyuk was published. At the same time, Samoilenko, together with his disciple M. O. Perestyuk, published the well-known monograph[4] devoted to the theory of impulsive differential equations. These monographs (especially their English translations[5][6][7]) are frequently cited in scientific literature.
Since 1987, Samoilenko has headed the Department of Ordinary Differential Equations at the Institute of Mathematics of the Academy of Sciences of the Ukrainian SSR (at present, the Department of Differential Equations and Theory of Oscillations at the Institute of Mathematics of the National Academy of Sciences of Ukraine), and since 1988 he has been the Director of the Institute of Mathematics of the National Academy of Sciences of Ukraine. The beginning of this fruitful creative period was marked by the fundamental monograph[8] devoted to the qualitative theory of invariant manifolds of dynamical systems. This monograph served as a foundation for the construction of the general perturbation theory of invariant tori of nonlinear dynamical systems on a torus. The English version[9] of this monograph is also well known. Three years later, the monograph[10] of Samoilenko (in coauthorship with Mitropol'skii and V. L. Kulyk) was published. In this monograph, in particular, the method of Lyapunov functions was used for the investigation of dichotomies in linear differential systems of the general form. The results of many-year investigations of constructive methods in the theory of boundary-valued problems for ordinary differential equations carried out by Samoilenko together with M. Ronto are presented in monographs.[11][12][13][14] Constructive algorithms for finding solutions of boundary-value problems with different classes of multipoint boundary conditions were developed by Samoilenko, V. M. Laptyns'kyi, and K. Kenzhebaev; the obtained results are presented in monograph.[15] Complex classes of resonance boundary-value problems whose linear pan cannot be described by Fredholm operators of index zero were investigated by Samoilenko, together with O. A. Boichuk and V. F. Zhuravlev, in monographs.[16][17] The monograph[18] of Samoilenko and Yu. V. Teplins'kyi is devoted to the theory of countable systems of ordinary differential equations. The monographs [19][20] of Samoilenko and R. I. Petryshyn cover a broad class of qualitative problems in the theory of nonlinear dynamical systems on a torus.
Samoilenko is the author of about 400 scientific works, including 30 monographs and 15 textbooks, most of which have been translated into foreign languages. His monographs made an important contribution to mathematical science and education. According to MathSciNet, the scientific papers of Samoilenko were cited 336 times by 208 authors.
The scientific interests of Samoilenko covered a broad range of important problems in the qualitative theory of differential equations, nonlinear mechanics, and the theory of nonlinear oscillations. His deep results in the theory of multifrequency oscillations, perturbation theory of toroidal manifolds, asymptotic methods of nonlinear mechanics, theory of impulsive systems, theory of differential equations with delay, and theory of boundary-value problems were highly appreciated in Ukraine and abroad. Academician Samoilenko was the founder of a scientific school in the theory of multifrequency oscillations and theory of impulsive systems recognized by the international mathematical community. His successful many-year guidance of the Institute of Mathematics of the Ukrainian National Academy of Sciences furthered the rapid development of mathematics in Ukraine and the continuation of the best traditions of the world-known Bogolyubov – Krylov – MitropolskiyKyiv scientific school.
The worldwide recognition of Samoilenko's mathematical results is illustrated by notions well known in the mathematical literature such as the Samoilenko numerical-analytic method and the Samoilenko – Green function (the kernel of an integral operator related to the problem of an invariant torus of a dynamical system).
Samoilenko gave much attention to training scientists of the highest qualification. For many years, he had given lectures at the Shevchenko Kyiv National University and the "Kyiv Polytechnic Institute" National Technical University and guided the scientific work of postgraduate and doctoral students. Despite the extremely busy schedule of his work as the Director of the Institute of Mathematics of the Ukrainian National Academy of Sciences for about 20 last years (since 2006, he was the Academician-Secretary of the Department of Mathematics at the National Academy of Sciences of Ukraine), Samoilenko found time for organizational and public activities. In particular, Samoilenko was the President of the "Foundation for Support of the Development of Mathematical Sciences" All-Ukrainian charity organization. Many young talents from the "small homeland" of Samoilenko (Malynshchyna) are grateful to him for founding and heading the charity foundation for support of the development of gifted children and youth.
Samoilenko found and taught many nonordinary scientists. He created an international scientific school in differential equations. Among his disciples, there are 33 doctors and 82 candidates of physical and mathematical sciences, who are now researchers of prestigious scientific institutions, professors, heads of chairs, deans, and rectors (scientific researchers, pedagogs, and administrators of various levels). For example, Samoilenko's alma mater (the Department of Mechanics and Mathematics at the Shevchenko Kyiv National University) has been headed for many years by his disciples (Professors M. O. Perestyuk and I. O. Parasyuk). Among other well-known scientists belonging to Samoilenko's mathematical school, one may mention Professor Kenzhebaev, the rector of the Zhubanov Aktobe University, one of the most reputable universities in Kazakhstan, and Academician M. Ilolov, the President of the Tajik Academy of Sciences.
^N. N. Bogolyubov, Yu. A. Mitropol’skii, and A. M. Samoilenko, Method of Accelerated Convergence in Nonlinear Mechanics [in Russian], Naukova Dumka, Kiev (1969).
^Yu. A. Mitropol’skii, A. M. Samoilenko, and D. I. Martynyuk, Systems of Evolution Equations with Periodic and Quasiperiodic Coefficients [in Russian], Naukova Dumka, Kiev (1984).
^A. M. Samoilenko and N. A. Perestyuk, Impulsive Differential Equations [in Russian], Vyshcha Shkola, Kiev (1987).
^N. N. Bogoljubov, J. A. Mitropolskii, and A. M. Samoilenko, Method of Accelerated Convergence in Nonlinear Mechanics, Hindustan Publishing Corporation, Delhi (1976).
^A. M. Samoilenko and N. A. Perestyuk, Impulsive Differential Equations, World Scientific, Singapore (1995).
^Yu. A. Mitropolsky, A. M. Samoilenko, and D. I. Martinyuk, Systems of Evolution Equations with Periodic and Quasiperiodic Coefficients, Kluwer, Dordrecht (1992).
^A. M. Samoilenko, Elements of the Mathematical Theory of Multifrequency Oscillations. Invariant Tori [in Russian], Moscow, Nauka (1987).
^A. M. Samoilenko, Elements of the Mathematical Theory of Multi-Frequency Oscillations, Kluwer, Dordrecht (1991).
^Yu. A. Mitropol’skii, A. M. Samoilenko, and V. L. Kulik, Investigation of Dichotomy of Linear Systems of Differential Equations Using Lyapunov Functions [in Russian], Naukova Dumka, Kiev (1990).
^A. M. Samoilenko and N. I. Ronto, Numerical-Analytic Methods in the Theory of Boundary-Value Problems for Ordinary Differential Equations [in Russian], Naukova Dumka, Kiev (1992).
^A. M. Samoilenko and N. I. Ronto, Numerical-Analytic Methods for the Investigation of Solutions of Boundary-Value Problems [in Russian], Naukova Dumka, Kiev (1986).
^A. M. Samoilenko and N. I. Ronto, Numerical-Analytic Methods for the Investigation of Periodic Solutions [in Russian], Vyshcha Shkola, Kiev (1976).
^M. Ronto and A. Samoilenko, Numerical-Analytic Methods in the Theory of Boundary-Value Problems, World Scientific, River Edge, NJ (2000).
^A. M. Samoilenko, V. N. Laptinskii, and K. K. Kenzhebaev, Constructive Methods for the Investigation of Solutions of Periodic and Multipoint Boundary-Value Problems [in Russian], Institute of Mathematics, Ukrainian National Academy of Sciences, Kiev (1999).
^A. A. Boichuk, V. F. Zhuravlev, and A. M. Samoilenko, Generalized Inverse Operators and Noetherian Boundary-Value Problems [in Russian], Institute of Mathematics, Ukrainian National Academy of Sciences, Kiev (1995).
^A. A. Boichuk and A. M. Samoilenko, Generalized Inverse Operators and Fredholm Boundary-Value Problems, VSP, Utrecht (2004).
^A. M. Samoilenko and Yu. V. Teplinskii, Countable Systems of Differential Equations, VSP, Utrecht (2003).
^A. M. Samoilenko and R. I. Petryshyn, Multifrequency Oscillations of Nonlinear Systems [in Ukrainian], Institute of Mathematics, Ukrainian National Academy of Sciences, Kyiv (1998).
^A. M. Samoilenko and R. I. Petryshyn, Mathematical Aspects of the Theory of Nonlinear Oscillations [in Ukrainian], Institute of Mathematics, Ukrainian National Academy of Sciences, Kyiv (2004).