Alfaprostol

Alfaprostol
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.070.657 Edit this at Wikidata
UNII
  • InChI=1S/C24H38O5/c1-29-24(28)12-8-3-2-7-11-20-21(23(27)17-22(20)26)16-15-19(25)14-13-18-9-5-4-6-10-18/h2,7,18-23,25-27H,3-6,8-14,17H2,1H3/b7-2-/t19-,20+,21+,22-,23+/m0/s1
    Key: OZDSQCVLNUIYLN-JNAAKWLTSA-N
  • COC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1C#C[C@H](CCC2CCCCC2)O)O)O
Properties
C24H38O5
Molar mass 406.56 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Alfaprostol is a bioactive analog of prostaglandin F2α. Alfaprostol is a luteolytic agent used injectably for scheduling of estrus in mares for purposes of planned breeding. It is also used for treating of postweaning anestrus in economically important farm animals. For these purposes, alfaprostol is more potent than naturally occurring prostaglandin F2α.

References

  • Boiti, C; Canali, C; Zerani, M; Gobbetti, A (1998). "Changes in refractoriness of rabbit corpora lutea to a prostaglandin F2 alpha analogue, alfaprostol, during pseudopregnancy". Prostaglandins & Other Lipid Mediators. 56 (4): 255–64. doi:10.1016/s0090-6980(98)00053-7. PMID 9777657.


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