On May 4, 2017, the 49ers signed Colbert to a four-year, $2.48 million contract that included a signing bonus of $84,786.[7] He played in 14 games with six starts at free safety as a rookie, recording 37 tackles and five passes defensed.
Colbert entered the 2018 season as the starting free safety for the 49ers. He played in seven games with six starts before suffering a high ankle sprain in Week 7. He was placed on injured reserve on October 22, 2018.[8]
Colbert was waived/injured during final roster cuts on August 31, 2019,[9] and reverted to the team's injured reserve list the next day. He was waived from injured reserve with an injury settlement on September 6.
Seattle Seahawks
On September 18, 2019, Colbert was signed to the practice squad of the Seattle Seahawks.[10] He was promoted to the active roster on September 26, 2019.[11] He was waived on October 12, 2019, and re-signed to the practice squad.[12]
Miami Dolphins
On November 19, 2019, Colbert was signed by the Miami Dolphins off the Seahawks practice squad.[13]
Colbert re-signed with the Dolphins on March 20, 2020.[14] He was waived on August 16, 2020.[15]
Kansas City Chiefs
Colbert was signed by the Kansas City Chiefs on August 22, 2020.[16] He was waived during final roster cuts on September 5, 2020.[17]
New York Giants
On September 6, 2020, Colbert was claimed off waivers by the New York Giants.[18] He was placed on injured reserve on November 3, 2020.[19] On December 19, 2020, Colbert was activated off of injured reserve.[20]
New England Patriots
On May 21, 2021, Colbert signed with the New England Patriots.[21] On August 30, 2021, Colbert was released by the Patriots.[22]
New York Jets
On September 6, 2021, Colbert was signed by the New York Jets to their practice squad.[23] He was promoted to the active roster on September 20.[24] On October 26, 2021, Colbert was released by the Jets.[25]
Cleveland Browns
On December 19, 2021, Colbert was signed to the Cleveland Browns practice squad.[26] He was elevated to the active roster as a COVID-19 replacement player on December 24, 2021.[27]
Tennessee Titans
On August 9, 2022, Colbert signed with the Tennessee Titans.[28] He was released on August 29, 2022.[29]
Chicago Bears
On November 29, 2022, Colbert was signed to the Chicago Bears practice squad.[30] He signed a reserve/future contract on January 9, 2023.[31] On August 21, 2023, Colbert was placed on injured reserve.[32] He was released with an injury settlement on August 30.[33] He was re-signed to the practice squad on November 21, 2023.[34] He signed a reserve/future contract on January 8, 2024.[35]
On August 27, 2024, Colbert was released by the Bears.[36] He was signed to the practice squad on November 20.[37]