The Detroit Tigers called Wilk up to the majors for the first time on May 24, 2011 when Phil Coke was placed on the 15-day disabled list with a bone bruise in his right foot.[5]
On May 26, 2011, Wilk made his major league debut against the Boston Red Sox, relieving Max Scherzer in the middle of the third inning. He pitched 3.2 innings, gave up one unearned run, struck out four batters, two hits, and one walk.[6]
On May 28, 2011, Wilk was optioned to Triple-A Toledo to make room for recently acquired David Purcey.[7]
NC Dinos
On December 19, 2012, Wilk's contact was sold by the Tigers to the Korean NC Dinos.[8] He signed a minor league deal with the Pittsburgh Pirates on December 18, 2013.[9]
Los Angeles Angels
Wilk signed a minor league deal with the Los Angeles Angels of Anaheim on December 5, 2014.[10] He was designated for assignment on July 25, 2015.[11]
Tampa Bay Rays
The Tampa Bay Rays signed Wilk to a minor league contract on January 19, 2016.[12] In 15 starts for the Triple–A Durham Bulls, he logged a 2–8 record and 3.61 ERA with 75 strikeouts across 87+1⁄3 innings pitched. Wilk elected free agency following the season on November 7.[13]
New York Mets
On January 12, 2017, Wilk signed a minor league contract with the New York Mets and was invited to spring training.[14] He was called up to the Mets on May 7,[15] and designated for assignment on May 8.
Minnesota Twins
The Minnesota Twins claimed Wilk on waivers on May 10, 2017.[16] He was designated for assignment on May 27, 2017,[17]
and outrighted to Triple-A two days later. On June 18, Wilk was again designated for assignment. He was released four days later.
Cleveland Indians
On January 20, 2018, Wilk signed a minor league contract with the Cleveland Indians.[18] In 27 starts for the Triple–A Columbus Clippers, he registered a 6–9 record and 3.66 ERA with 107 strikeouts across 164+2⁄3 innings pitched. Wilk elected free agency following the season on November 2.[19]
Personal life
Wilk was noted for his community involvement while with the Toledo Mud Hens. In the 2012–2013 offseason, he began his own non-profit organization, the Adam Wilk Foundation.[20]