Actinomyces-1 RNA motif


Actinomyces-1
Consensus secondary structure and sequence conservation of Actinomyces-1 RNA
Identifiers
SymbolActinomyces-1
RfamRF02928
Other data
RNA typeGene; sRNA
SOSO:0001263
PDB structuresPDBe

The Actinomyces-1 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] Actinomyces-1 motifs are found in the genus Actinomyces, in the phylum Actinomycetota. Actinomyces-1 RNAs likely function in trans as sRNAs. In terms of their secondary structure, Actinomyces-1 RNAs consist of a multistem junction with many conserved GA dinucleotides.

Actinomyces-1 RNAs contain a predicted kink turn.[2] This particular example of a kink turn was studied to better understand how kink turn structures relate to their sequences.

References

  1. ^ Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Research. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.
  2. ^ Huang L, Liao X, Li M, Wang J, Peng X, Wilson TJ, Lilley DM (June 2021). "Structure and folding of four putative kink turns identified in structured RNA species in a test of structural prediction rules". Nucleic Acids Res. 49 (10): 5916–5924. doi:10.1093/nar/gkab333. PMC 8191799. PMID 33978763.