The methanol extract of Aaptos aaptos has been found to reduce the antioxidants in cancer cells, which increases oxidative stress selectively in cells which contributes to their antiproliferative effects.[5]
^Schmidt, E.O. (1864) Supplement der Spongien des adriatischen Meeres. Enthaltend die Histiologie und systematische Ergänzungen. Leipzig : Engelmann 48 pp. 4 pls. [33].
^Meylan, Anne (1988-01-12). "Spongivory in Hawksbill Turtles: A Diet of Glass". Science. 239 (4838). American Association for the Advancement of Science: 393–395. doi:10.1126/science.239.4838.393. JSTOR1700236. PMID17836872.
^Shiau, Jun-Ping; Lee, Min-Yu; Tang, Jen-Yang; Huang, Hsin; Lin, Zheng-Yu; Su, Jui-Hsin; Hou, Ming-Feng; Cheng, Yuan-Bin; Chang, Hsueh-Wei (2022-12-16) [Published December 16, 2022]. "Marine Sponge Aaptos suberitoides Extract Improves Antiproliferation and Apoptosis of Breast Cancer Cells without Cytotoxicity to Normal Cells In Vitro". Pharmaceuticals: 19 – via MDPI.{{cite journal}}: CS1 maint: year (link)