The aspiring surgeon María Alejandra Rivas (Verónica Orozco) is admitted to the program for interns at the Hospital Universitario of Santa María. Daughter of one of the most famous surgeons of her time, now Alzheimer's diseased, Maria Alejandra should bear the responsibility that gives her his last name. His group of new friends, Jorge Viana (Juan Manuel Mendoza), Cristina Solano (Natalia Durán), Isabel Henao (Sandra Hernández) and Augusto Maza (Juan Pablo Espinosa), will from now on become their new family. María Alejandra faces the loneliness helped by these new people and by the sentimental relationship that she establishes with Andrés Guerra (Rafael Novoa), one of the best surgeons of the hospital.
On April 26, 2010, A Corazón Abierto premiered in Colombia to excellent ratings. With a 20.4 rating and 48 share, almost half the television viewing audience in Colombia watched the premiere.[1]
