4-Hydroxymandelic acid is a chemical compound used to synthesize atenolol.[1] The compound typically occurs as a monohydrate.
It is produced from 4-hydroxypyruvic acid by the action of the enzyme (S)-p-hydroxymandelate synthase:
4-Hydroxymandelic acid can be synthesized by the condensation reaction of phenol and glyoxylic acid:[1]
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