The women's 50m butterfly events at the 2023 World Para Swimming Championships were held at the Manchester Aquatics Centre between 31 July and 6 August.

Event	Gold	Silver	Bronze
S5	Lu Dong  China	He Shenggao  China	Sevilay Öztürk  Turkey
S6	Jiang Yuyan  China	Verena Schott  Germany	Elizabeth Marks  United States
S7	Danielle Dorris  Canada	Tess Routliffe  Canada	Julia Gaffney  United States

Heats

Ten swimmers from seven nations took part. The swimmers with the top eight times, regardless of heat, advanced to the final.^[1]

Rank	Heat	Lane	Name	Nation	Result	Notes
1	2	5	He Shenggao	China	44.21	Q
2	1	4	Sevilay Öztürk	Turkey	44.37	Q
3	2	4	Lu Dong	China	45.27	Q
4	2	3	Cheng Jiao	China	46.32	Q
5	1	6	Angel Mae Otom	Philippines	46.83	Q
6	1	5	Esthefany Rodrigues	Brazil	47.41	Q
7	1	3	Giulia Ghiretti	Italy	48.64	Q
8	2	2	Darlin Jiseb Romero Sanchez	Colombia	51.67	Q
9	1	2	Dunia Felices	Peru	1:04.07
	2	6	Sümeyye Boyacı	Turkey	DSQ

Final

The final was held on 2 August.^[2]

Rank	Athlete	Nation	Result	Notes
	Lu Dong	China	39.94	CR
	He Shenggao	China	40.09
	Sevilay Öztürk	Turkey	43.87
4	Cheng Jiao	China	46.44
5	Esthefany Rodrigues	Brazil	46.66
6	Angel Mae Otom	Philippines	47.52
7	Giulia Ghiretti	Italy	47.99
8	Darlin Jiseb Romero Sanchez	Colombia	51.82