Wheelchair women's singles
2021 Wimbledon Championships
Final
Champion	Diede de Groot
Runner-up	Kgothatso Montjane
Score	6–2, 6–2
Details
Draw	8
Seeds	2
Events
Singles men women boys girls Doubles men women mixed boys girls WC Singles men women quad WC Doubles men women quad
← 2019 · Wimbledon Championships · 2022 →

Diede de Groot defeated Kgothatso Montjane in the final, 6–2, 6–2 to win the ladies' singles wheelchair tennis title at the 2021 Wimbledon Championships. It was her third Wimbledon singles title, completed a non-calendar-year Grand Slam, and was the third step in an eventual Super Slam.

Aniek van Koot was the defending champion from when the event was last held in 2019,^[1] but was defeated in the quarterfinals by Jordanne Whiley.

	Quarterfinals							Semifinals							Final
	1	Diede de Groot	6	6
	WC	Lucy Shuker	4	1
								1	Diede de Groot	6	6
									Jordanne Whiley	4	1
		Aniek van Koot	2	0
		Jordanne Whiley	6	6
															1	Diede de Groot	6	6
																Kgothatso Montjane	2	2
		Kgothatso Montjane	6	2	6
		Angélica Bernal	1	6	4
									Kgothatso Montjane	77	4	6
									Momoko Ohtani	63	6	4
		Momoko Ohtani	6	6
	2	Yui Kamiji	3	4

• WC Women's Singles